Plot

The following synopsis covers each route of the three paths in Pathologic Classic. This is not a spoiler free walkthrough! This only covers the relevant plot details and should not serve as a walkthrough. With information taken from the official Pathologic Classic guide created by Halfgild Wynac, this may serve as an overview of the story's events.

Summary
The events of Pathologic take place over the course of twelve days in the remote Town-on-Gorkhon on the Steppe. When an outbreak of a unique strain of Plague grips the town, three healers—a Bachelor of medicine, a Haruspex surgeon, and a blessed Changeling—must race to discover the cause of the Plague and destroy it.

The Bachelor's Path
Daniil Dankovsky, a Bachelor of Medicine, was brought here by circumstances most unfortunate. Dankovsky's lifework, his theory challenging the existing notions of human mortality, is being harshly persecuted by the Powers That Be. Suddenly a letter arrives from a colleague, suggesting that there is previously undiscovered evidence which may support Dankovsky's claims. There is a settlement, the letter says, ruled by an extraordinary man who may well be seen as objective proof of Dankovsky's daring hypothesis. Grasping at straws of hope, Dankovsky decides to follow what he believes to be a sign of divine providence. Without further ado, he sets off for the settlement.

Day 1
Daniil Dankovsky wakes in the Stillwater, Eva Yan home. He heads downstairs and aqcuaintances himself with the owner of the house, to which she notes she heard something outside her window, which appears to be two squatters in her yard. Daniil will head to speak with Simon Kain, and heads to the Crucible, the house of the Kains.

However, when Daniil arrives, he discovers that Simon has been murdered by an "inhuman force". His twin brother, Georgiy Kain, speaks with him on what happened the night before, as does Victor Kain, the youngest of the brothers. Daniil learns that shortly before his death Simon was visited by Isidor Burakh; a healer who was respected throughout town, and the man that invited Daniil to the town.

Daniil marches across town to visit Isidor, but sees volunteer patrolmen standing outside of his house. It seems that Isidor, too, is dead, having been murdered the night before. Though none may inspect his body, it is suspected that Isidor's own son, Artemy Burakh, killed him. Saburov speaks with Daniil about how Isidor came to speak with him before his murder, suspecting that he wanted to talk about his eventual succession to leading the Kin. Therefore, he highly suspects Artemy to be responsible. After speaking with Dankobsky for some time, Saburov sends him to speak with a mathematician named Yulia Lyuricheva who may know more. Once Daniil meets with her, she tells him that Isidor has visited Simon late at night as well, and has returned to the town before dark. It is likely that he spoke with Vlad Olgimsky Sr, the industrial leader of town who worked with Isidor at times.

Daniil visits his abode, called the Lump. But it seems that he doesn’t want to talk about Isidor. Instead, he spends his time cursing about his son, who has been sympathizing with the indigenous Steppe people of town. After leaving the older Olgimsky, Daniil is brought to his son's house by a Worm, a brick building with covered windows. He speaks with Vlad the Younger, who tells about how Isidor came to their house to speak about a possible sickness that was starting. His father allegedly didn't believe him, but Vlad the Younger had the Termitary - the large housing block of workers - locked in turn to prevent any risk of infection.

It becomes evident to Dankovsky that Simon died of the same illness that killed Isidor. He is told about how Stanislav Rubin, the protege of Isidor, wants to examine the body – who Daniil knows he must warn. He seeks out Rubin at the house of the Kains, where they speak about their next step.

The Haruspex's Path
Haruspex returns to the Town after receiving a letter from his father, Isidor Burakh, who fears that his death is imminent. Haruspex intends to see his father before his passing, and to receive his inheritance: a place of authority in the Order. However, arriving at the Train Station, Haruspex is descended upon by a vicious mob that believes him to be a recent serial killer. Haruspex manages to cut down several people, but must flee before he is overcome. Injured, Haruspex vaults a fence and stumbles into a seemingly-innocuous warehouse.

The Changeling's Path
Changeling awakens in a freshly-dug grave, uncertain of where or why she is. She is beset by visions of a mirror image of herself—a twin?