Lotman and Siskin

Lotman and Siskin are characters from Pathologic: The Marble Nest.

Pathologic: The Marble Nest
The Bachelor finds Lotman and Siskin in the Silent House discovered by Sleepy Head, Shrew, and Sticky. Bachelor quickly realizes that Lotman and Siskin are the carriers that he's been looking for; however, both are delirious with fever and refuse to reveal how they contracted the Sand Plague. Instead, they tell Bachelor that the Plague is the key to immortality. Bachelor subsequently orders their quarantine.